环境中的药物

病人排泄, improper disposal of unused medicines and discharges from drug production result in the release of active pharmaceutical ingredients (APIs) into the environment. Potential impacts include effects on wildlife and human health from low-level and/or long-term exposure.

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澳门葡京赌博游戏的方法

澳门葡京赌博游戏在pie相关主题的管理方面处于行业领先地位. We were the first company to publish discharge limit targets for drug production and formulation facilities that were externally verified. 澳门葡京赌博游戏也是第一家发行游戏的公司 环境风险评估 数据在澳门葡京赌博游戏的网站上,澳门葡京赌博游戏是唯一的公司与一个 发布方法 生态药物警戒(EPV). EPV ensures that we review emerging information that might change the way we assess and manage the environmental risks of our medicines. 在下面的部分中阅读有关澳门葡京赌博游戏管理PIE的具体方法的更多信息.

在许多情况下,环境中没有检测到澳门葡京赌博游戏的api. 当澳门葡京赌博游戏的api被检测到时, in almost all cases these APIs have been shown via our EPV process to pose low or insignificant environmental risk. 对于特定的药物,可能存在一些特定地点的环境风险, especially in regions w在这里 t在这里 may be inadequate sewage treatment and high populations of people discharging waste into rivers with low dilution conditions. 澳门葡京赌博游戏正在进行的EPV监测全球人口是否增加, 人口老龄化, 增加低收入和中等收入国家获得药品的机会, 城市化和/或疾病流行病学的变化将在未来改变这些风险.

AstraZeneca works in partnership with academic thought leaders to develop new tools and knowledge to help understand the environmental risk that pharmaceuticals pose. 澳门葡京赌博游戏还致力于支持下一代环境科学家. 在任何时候, we support around ten PhD students in collaboration with United Kingdom Research Innovation, who are conducting research on critical issues that underpin the protection of our natural environment. 澳门葡京赌博游戏致力于推进PIE科学并继续生产 科学出版物 在这个领域.


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空气污染指数安全排放计划


药品生产产生的废物可能是当地的污染, intermittent issue that is within our control and t在这里fore it is important we manage this. 目前还没有, 或几, 区域监管要求, we run a ‘Safe API Discharge’ programme for both our production sites and those of our suppliers. 澳门葡京赌博游戏是透明的 方法 澳门葡京赌博游戏跟着 排放浓度指标 澳门葡京赌博游戏已经为澳门葡京赌博游戏的api建立了,澳门葡京赌博游戏支持并遵循 IAI技术指导文件 负责任的生产废水管理的实施. 澳门葡京赌博游戏为每种API指定两个排放浓度, 一个是长期暴露, 环境参考浓度(ERC), 另一种是短期接触,称为最大耐受浓度(MTC). 如果一个地点发现超过了这些参考浓度中的任何一个, 澳门葡京赌博游戏会进行彻底的调查,并采取必要的纠正措施. 澳门葡京赌博游戏为空气污染排放设定了可测量的指标, 并在澳门葡京赌博游戏的年度可持续发展报告中报告这些情况. 





EcoPharmacoVigilance仪表板


由于病人使用和制造, 药物是在水生环境中发现的, 通常在 毫微克每升的浓度. AstraZeneca conducts a robust environmental risk assessment for its products in addition to our Safe API Discharge programme for 生产设备.

作为其正在进行的一部分 EcoPharmacoVigilance 澳门葡京网赌游戏也承担季度Search已发表的, peer-reviewed scientific literature for reports of detection of environmental residues of our active pharmaceutical ingredients (APIs) in order to understand real world environmental risks. Of 40 APIs included in the search, reports of measured data have been found for 32 of those APIs. 的se measured environmental concentrations (MECs) have been extracted and formatted for transparent visualization. 的 EcoPharmacoVigilance仪表板 presents these MECs in a risk relationship relative to the Predicted No Effect Concentrations (PNECs) used for environmental assessment. 计算出的rq显示为0.0表示风险商小于1x10-9.

This dashboard was last updated in February 2024 based on literature searches performed up to Q3 2023 and now has 49,089个数据条目.

EcoPharmacoVigilance仪表板是与Simomics公司联合开发的. To get the best experience, we recommend using the latest version of Chrome, Edge, Safari or Firefox.



澳门葡京赌博游戏的故事