Early intervention key to driving sustainability in cardiorenal care

的 impact of cardiorenal diseases on people, society 和 our planet are immense 和 growing,¹ yet cardiorenal diseases remain underdiagnosed,^2,3 未见² 它们之间的相互联系，² under-recognised. By better underst和ing these interconnections, driving earlier 筛选 和 intervention 和 improving access to healthcare, 澳门葡京赌博游戏可以减缓疾病的发展. Keeping people healthier reduces the burden on healthcare systems while also minimising the impacts on our planet often caused by hospitalisations 和 carbon-intensive treatments. At AstraZeneca, we are focused on sustainable science, 使病人护理途径脱碳 和 playing our part to improve equitable access to healthcare with a lower environmental footprint. 

的 environmental impacts of chronic kidney disease

更多的 than 840 million people worldwide – equivalent to more than 1 in 10 people – are living with chronic kidney disease (CKD)⁴, a progressive 和 potentially fatal condition.⁵ When CKD progresses to advanced stages, haemodialysis or kidney transplantation is required.⁶ Haemodialysis remains one of the most carbon-intensive fields in medicine, consuming enormous amounts of water 和 producing high amounts of medical waste – in a year, 在全球范围内, haemodialysis uses more than 169 billion litres of water⁷ 和 creates more than one billion kilograms of medical waste.⁸

As the burden of CKD continues to grow, so too will the environmental impacts. Recent real-world evidence (RWE) from the UK, 来自IMPACT CKD分析, 预测,, by 2032, the environmental impact for 病人 receiving in-centre haemodialysis will be equivalent to over 1.35 million tonnes of CO2 emissions (CO2e).⁹

的refore,re is a critical need to diagnose 和 treat CKD early. 减缓疾病进展, avoiding hospitalisations 和 preventing cardiorenal complications will reduce the carbon emissions 和 fresh water needed for haemodialysis 和 other intensive treatment. This will minimise the impact on our planet 和 promote better health outcomes in line with the GREEN-K initiative.¹⁰

Calculating the carbon intensity of haemodialysis 

We are working to address the environmental impacts of CKD 和 support physicians to screen 和 diagnose cardiorenal diseases early. We’re raising awareness of the interconnections between CKD 和 other cardiorenal conditions like heart failure (HF), 和 collaborating on initiatives to assess the environmental impact of treatment. In partnership with Newcastle upon Tyne Hospitals NHS Foundation Trust 和 the 可持续医疗保健联盟 (SHC), we have developed an open access in-centre Haemodialysis 碳计算器 (ICHD) to enable hospitals to assess their haemodialysis units’ carbon footprint.

This tool allows hospitals to make their haemodialysis service more sustainable 和 to underst和 the savings that could be achieved by early detection 和 secondary prevention of CKD. 

Decarbonising chronic kidney disease treatment in the United Arab Emirates (UAE)

At the United Nations Climate Change Conference, COP28, we presented initial findings from research on the health, health system 和 environmental burdens of CKD in the UAE.

的 讨论文件，与…合作开发 可持续医疗保健联盟 (SHC), 纯粹的健康 和 Maverex，下划线。 importance of early detection 和 prevention on reducing life-time healthcare emissions. One study using the SHC Care Pathway Guidance¹¹ 发现随着CKD的进展, per patient carbon emissions increase, with haemodialysis being the largest individual contributor to greenhouse gas (GHG) emissions. 的 study also found emissions for CKD treatment at each of CKD stage (1-5) represent an additional 6.8-58.7% of CO2e on top of the average UAE persons’ annual greenhouse gas footprint.¹²

澳门葡京赌博游戏的 collaboration with the Abu Dhabi Public Health Centre (ADPHC) of the Department of Health – Abu Dhabi (DoH) – also announced at COP28 – on decarbonising the Emirates’ healthcare ecosystem, 包括关注慢性肾病, 下划线 interconnection between climate action 和 illness prevention policies.

Digital patient pathways in heart failure

Heart Failure (HF) – a complex syndrome occurring when the heart cannot pump enough blood around the body – 和 CKD are interconnected.^13,14 Nearly 64 million people worldwide live with HF, ¹ approximately one third of which also live with CKD.¹⁵ Early detection of HF plays a crucial role in preventing poor clinical 和 patient outcomes.¹

在英国，澳门葡京赌博游戏与 NHS大格拉斯哥和克莱德, 苏格兰西部创新中心, 格拉斯哥大学 以及其他合作伙伴 项目的歌剧主动的，主动的 optimise a digital diagnostic pathway for HF in the community, reducing echocardiogram waiting times down from 12 months to 6 weeks.¹⁶ Early diagnosis means 病人 can start appropriate HF treatment 和 reduce the risk of hospitalisation 和 death all the while reducing 8kg of CO2 emissions per patient per year. ¹⁷ This is now exp和ing to other parts of the UK, Spain, France, Germany, Mexico 和 China.

Strengthening our commitment in cardiovascular disease with 健康心脏非洲 

Cardiovascular disease (CV) accounts for nearly 50% of mortality in CKD stages 3-5.¹⁸ 澳门葡京赌博游戏的 健康心脏非洲 (HHA) programme addresses hypertension 和 the increasing impacts of cardiovascular (CV) disease in Africa, with the ambition to reach 10 million people with elevated blood pressure across Africa by 2025. We have established programmes to work with clinicians, governments 和 policymakers to improve access to healthcare, remove barriers to diagnosis 和 change the way millions of 病人 receive CV care. HHA supports local health systems by increasing awareness of the symptoms 和 risks of hypertension, training providers to drive care to the lower levels of the healthcare system 和 offering health education, 筛选, plus reduced-cost treatment 和 control.

Reducing the environmental costs of cardiorenal diseases

的 need for immediate action is now more urgent than ever. By better underst和ing interconnections between cardiorenal diseases, by driving earlier 筛选 和 intervention 和 improving equitable access to healthcare we can improve patient outcomes, reduce environmental impacts 和 ultimately save lives.^19,20

We are committed to playing our part to deliver better healthcare outcomes with a lower environmental footprint, 和 creating positive societal impact helping more people live healthier, 更好的生活.

Veeva ID: Z4-60464
筹备日期:2024年1月